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By incorporating phenotypic traits of their two original species, yeast hybrids exhibit a unique combination of properties and an array of fermentation products. For example, wine yeast hybrids can combine the low temperature tolerance of one parent with the profile of volatile molecules (aromas) produced by the other. This project will first aim to generate new Saccharomyces interspecies hybrids with metabolic phenotypes of interest for the wine industry. The second key point will be the identification of the metabolic network and genetic loci responsible for fermentative characters and formation of aroma and flavour by these strains.

Ce projet a été financé par le programme de recherche et d'innovation Horizon 2020 de l'Union européenne dans le cadre de la convention de subvention Marie Skłodowska-Curie n ° 764927.

> Période: 01/07/2019 au 30/06/2022

> Directeurs de thèse: Sylvie Dequin (INRAE Montpellier, UMR SPO) & Ed Louis (University of Leicester, UK)

> Encadrante : Carole Camarasa (INRAE Montpellier, UMR SPO)

> Contact: rafael.alvarez-rafael@inrae.fr